Transcranial Magnetic Stimulation (TMS)

Scientific Publications

TMS therapy, particularly when combined with Psychotherapy, can be an efficacious treatment option for patients with depression and OCD. Many patients ask for this neurostimulation treatment as an alternative to medications. TMS has been scientifically proven to deliver fast antidepressant effects and is considered an effective alternative to treat Depression. Furthermore, there are little to no side-effects reported. On this page, you will find several scientific publications which highlight the benefits of TMS therapy and the science behind its clinical use today throughout the world and in Australia.

Donse et al. 2018

Simultaneous rTMS and psychotherapy in major depressive disorder clinical outcomes and predictors from a large naturalistic study

This study shows that combining rTMS with Psychotherapy (as per protocol in neuroCare Clinics) is more effective than either therapy alone. In this study of 196 patients, 66% of patients with Treatment-Resistant Depression, responded well to TMS therapy when combined with Psychotherapy, after an average of 21 sessions. Furthermore, lasting effects are noticed after 6 months in 65% of this group. This suggests that the combined approach of combining this neurostimulation treatment with talk therapies improves the likelihood of a patient achieving a complete remission of Depression.

O’Reardon, J.P., 2007

Efficacy and Safety of Transcranial Magnetic Stimulation in the Acute Treatment of Major Depression: A Multisite Randomized Controlled Trial

The first randomised, multi-centre, double-blind placebo-controlled study of rTMS in the treatment of depression. This study was pivotal in achieving FDA approval in the USA for rTMS.

Donse et al. 2017

Sleep disturbances in obsessive-compulsive disorder: Association with non-response to repetitive transcranial magnetic stimulation (rTMS)

This study shows the first results of rTMS used in treatment-resistant OCD where 55% of patients responded to treatment. Further, sleep onset problems were found as a reliable predictor for non-response to rTMS.

George et al. 2010

Daily Left Prefrontal Transcranial Magnetic Stimulation Therapy for Major Depressive Disorder

An independent NIMH funded replication of the O’Reardon study (2007) which confirms the efficacy of rTMS in the treatment of Depression.

Schutter 2010

Quantitative review of the efficacy of low-frequency magnetic brain stimulation in major depressive disorder

This is a meta-analysis which demonstrates the efficacy of low-frequency rTMS in the treatment of Depression.

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